Department
Applications are invited for a post-doctoral researcher to join the group of Dr Cécile Crosnier in the Department of Biology and the York Biomedical Research Institute (YBRI) at the University of York (https://www.york.ac.uk/biology/our-staff/dr-cecile-crosnier). The research project will investigate host:parasite interactions during the host immune response to Schistosoma mansoni infections. The position is funded by an MRC Career Development award, initially for three years with possibility for contract extension. You will have access to the outstanding Bioscience Technology Facility, which offers access to a wide range of state-of-the-art imaging, proteomics, genomics and bioinformatics services. The Department of Biology is one of the largest departments at the University of York and delivers world-class science. Your research will have a strong focus on mechanisms of immunomodulation in the context of neglected tropical diseases and aligns with the Immunology, Haematology and Infection research theme of YBRI.
Role
The laboratory is looking for a talented, enthusiastic and highly-motivated post-doctoral research associate with a strong interest in host:parasite interactions and immunology. You will be expected to conduct individual and collaborative research projects both within the Department of Biology and with external collaborators to further our understanding of the molecular mechanisms used by the helminth Schistosoma mansoni to establish chronic infections in its human host. You will use a range of biochemical and cellular approaches to investigate host:parasite protein:protein interactions involved in host immune modulation during infection. You will also use serological studies to investigate the host humoral response associated with protection from re-infection.
Skills, Experience & Qualification needed
- PhD in Biology, Microbiology, Biochemistry, Immunology or related areas, or equivalent experience
- Knowledge in parasitology, immunology and/or biochemistry to engage in high quality research
- Knowledge of a range of research techniques and methodologies including tissue culture, molecular biology, recombinant protein production and purification, cell-based immune assays
- Experience in mammalian and/or insect cell culture, molecular biology and biochemistry; additional experience in flow cytometry, cellular immune assays and/or surface plasmon resonance is desirable
- Ability to develop research objectives, projects and proposals for own and joint research
- Ability to write up research work for publication and engage in public dissemination
- Attention to detail and commitment to high quality
Interview date (provisional): 4th July 2023
For informal enquiries: please contact Cécile Crosnier (cecile.crosnier@york.ac.uk)
The University strives to be diverse and inclusive – a place where we can ALL be ourselves.
We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.
We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork
